ChemicalBook > CAS DataBase List > 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER

Product Name
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
CAS No.
16600-22-9
Chemical Name
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms
NSC 403048;3-Carbethoxy-4-hydroxy-7-chloroquinoline;Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate;Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate;Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate;ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate;Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester;7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester;7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
CBNumber
CB2234544
Molecular Formula
C12H10ClNO3
Formula Weight
251.67
MOL File
16600-22-9.mol
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7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Property

Melting point:
296-298℃
Boiling point:
366.8±37.0 °C(Predicted)
Density 
1.386
storage temp. 
Sealed in dry,Room Temperature
pka
2.18±0.50(Predicted)
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Safety

HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0036646
Product name
ETHYL 7-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLATE
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
Ambeed
Product number
A157673
Product name
Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
Purity
95+%
Packaging
5g
Price
$1031
Updated
2021/12/16
Alichem
Product number
16600229
Product name
Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
Packaging
5g
Price
$1177.66
Updated
2021/12/16
Alichem
Product number
16600229
Product name
Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
Packaging
10g
Price
$1633.66
Updated
2021/12/16
Alichem
Product number
16600229
Product name
Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
Packaging
25g
Price
$2833.56
Updated
2021/12/16
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7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Crystalline compounds. Melting point 297 ℃.

Uses

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine.

Synthesis

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil.

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Mineral oil N-2,4-DIMETHYLPHENYL-N'-METHYLFORMAMIDINE 3-Chloroaniline

Preparation Products

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7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Suppliers

China 21 India 1 Switzerland 1 The Netherlands 1 United States 2 Global 26
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58

16600-22-9, 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTERRelated Search:

Hydrochlorothiazide QUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-4-HYDROXY QUINOLINE-3-CARBOXYLIC ACID 4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER 7,8-DICHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ETHYL 7-CHLORO-6-FLUORO-4-HYDROXY-3-QUINOLINECARBOXYLATE ETHYL 5,7-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE Ethyl 7-chloro-4-hydroxy-8-methylquinoline-3-carboxylate SALOR-INT L100110-1EA

  • 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
  • Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
  • 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester
  • 3-Carbethoxy-4-hydroxy-7-chloroquinoline
  • Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate
  • 4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester
  • ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate
  • Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate
  • NSC 403048
  • Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate
  • 7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester
  • 16600-22-9